Characterization of the roles of SH2 domain-containing proteins in T-lymphocyte activation by using dominant negative SH2 domains.

Activation of the T-cell antigen receptor initiates a complex signaling cascade leading to changes in cytokine gene transcription. Several proteins containing Src homology 2 (SH2) domains, capable of interacting with phosphotyrosine-containing sequences within other proteins, are involved in the act...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Northrop, J P, Pustelnik, M J, Lu, A T, Grove, J R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231213/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8628292/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.5.2255
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