Erythropoietin induces activation of Stat5 through association with specific tyrosines on the receptor that are not required for a mitogenic response.

The cytoplasmic domain of the erythropoietin receptor (EpoR) contains a membrane-distal region that is dispensable for mitogenesis but is required for the recruitment and tyrosine phosphorylation of a variety of signaling proteins. The membrane-proximal region of 96 amino acids is necessary and suff...

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Detalhes bibliográficos
Main Authors: Quelle, F W, Wang, D, Nosaka, T, Thierfelder, W E, Stravopodis, D, Weinstein, Y, Ihle, J N
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC231148/
https://ncbi.nlm.nih.gov/pubmed/8657137
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