ApoE2-associated hypertriglyceridemia is ameliorated by increased levels of apoA-V but unaffected by apoC-III deficiency

Apolipoprotein E2 (apoE2)-associated hyperlipidemia is characterized by a disturbed clearance of apoE2-enriched VLDL remnants. Because excess apoE2 inhibits LPL-mediated triglyceride (TG) hydrolysis in vitro, we investigated whether direct or indirect stimulation of LPL activity in vivo reduces the...

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Detaylı Bibliyografya
Asıl Yazarlar: Gerritsen, Gery, van der Hoogt, Caroline C., Schaap, Frank G., Voshol, Peter J., Kypreos, Kyriakos E., Maeda, Nobuyo, Groen, Albert K., Havekes, Louis M., Rensen, Patrick C. N., van Dijk, Ko Willems
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2008
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2311447/
https://ncbi.nlm.nih.gov/pubmed/18263930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M800009-JLR200
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