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Thematic Review Series: Sphingolipids. Ganglioside GM3 suppresses the proangiogenic effects of vascular endothelial growth factor and ganglioside GD1a

Gangliosides are sialic acid-containing glycosphingolipids that have long been associated with tumor malignancy and metastasis. Mounting evidence suggests that gangliosides also modulate tumor angiogenesis. Tumor cells shed gangliosides into the microenvironment, which produces both autocrine and pa...

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Detalhes bibliográficos
Main Authors: Mukherjee, Purna, Faber, Anthony C., Shelton, Laura M., Baek, Rena C., Chiles, Thomas C., Seyfried, Thomas N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2311436/
https://ncbi.nlm.nih.gov/pubmed/18287616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.R800006-JLR200
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