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Synthetic enhancement of a TFIIB defect by a mutation in SSU72, an essential yeast gene encoding a novel protein that affects transcription start site selection in vivo.

An ssu72 mutant of Saccharomyces cerevisiae was identified as an enhancer of a TFIIB defect (sua7-1) that confers both a cold-sensitive growth defect and a downstream shift in transcription start site selection. The ssu72-1 allele did not affect cold sensitivity but, in combination with sua7-1, crea...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Principais autores: Sun, Z W, Hampsey, M
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 1996
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231141/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8657130/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.4.1557
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