The sua8 suppressors of Saccharomyces cerevisiae encode replacements of conserved residues within the largest subunit of RNA polymerase II and affect transcription start site selection similarly to sua7 (TFIIB) mutations.

Mutations in the Saccharomyces cerevisiae sua8 gene were found to be suppressors of an aberrant ATG translation initiation codon in the leader region of the cyc1 gene. Analysis of cyc1 transcripts from sua8 mutants revealed that suppression is a consequence of diminished transcription initiation at...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Berroteran, R W, Ware, D E, Hampsey, M
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 1994
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358373/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8264591/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.1.226
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