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Linking functionally related genes by sensitive and quantitative characterization of genetic interaction profiles

Describing at a genomic scale how mutations in different genes influence one another is essential to the understanding of how genotype correlates with phenotype and remains a major challenge in biology. Previous studies pointed out the need for accurate measurements of not only synthetic but also bu...

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Hlavní autoři: Decourty, Laurence, Saveanu, Cosmin, Zemam, Kenza, Hantraye, Florence, Frachon, Emmanuel, Rousselle, Jean-Claude, Fromont-Racine, Micheline, Jacquier, Alain
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2311358/
https://ncbi.nlm.nih.gov/pubmed/18408161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710533105
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