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Raf, but not MEK or ERK, is sufficient for differentiation of hippocampal neuronal cells.

To elucidate signal transduction pathways leading to neuronal differentiation, we have investigated a conditionally immortalized cell line from rat hippocampal neurons (H19-7) that express a temperature sensitive simian virus 40 large T antigen. Treatment of H19-7 cells with the differentiating agen...

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Bibliographic Details
Main Authors: Kuo, W L, Abe, M, Rhee, J, Eves, E M, McCarthy, S A, Yan, M, Templeton, D J, McMahon, M, Rosner, M R
Format: Artigo
Language:Inglês
Published: 1996
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC231130/
https://ncbi.nlm.nih.gov/pubmed/8657119
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