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Inhibition of androgen-independent prostate cancer cell growth is enhanced by combination therapy targeting Hedgehog and ErbB signalling

BACKGROUND: Prostate cancer is a leading cause of male cancer specific mortality. When cure by radical prostatectomy is not possible the next line of prostate cancer treatment is androgen deprivation. However prolonged androgen deprivation often results in relapse and androgen-independent prostate c...

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Bibliographic Details
Main Authors: Shaw, Greg, Prowse, David M
Format: Artigo
Language:Inglês
Published: BioMed Central 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2311276/
https://ncbi.nlm.nih.gov/pubmed/18348720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-8-3
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