Phosphorylation of IkappaBalpha in the C-terminal PEST domain by casein kinase II affects intrinsic protein stability.

Gelijkaardige items

• Constitutive phosphorylation of IkappaBalpha by casein kinase II occurs preferentially at serine 293: requirement for degradation of free IkappaBalpha.
  door: Schwarz, E M, et al.
  Gepubliceerd in: (1996)
• An N-terminal nuclear export signal is required for the nucleocytoplasmic shuttling of IkappaBalpha.
  door: Johnson, C, et al.
  Gepubliceerd in: (1999)
• IkappaBalpha deficiency results in a sustained NF-kappaB response and severe widespread dermatitis in mice.
  door: Klement, J F, et al.
  Gepubliceerd in: (1996)
• Chronic human immunodeficiency virus type 1 infection of myeloid cells disrupts the autoregulatory control of the NF-kappaB/Rel pathway via enhanced IkappaBalpha degradation.
  door: DeLuca, C, et al.
  Gepubliceerd in: (1996)
• IkappaBalpha gene promoter polymorphisms are associated with hepatocarcinogenesis in patients infected with hepatitis B virus genotype C
  door: He, Yongchao, et al.
  Gepubliceerd in: (2009)