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Effects of reverse transcriptase inhibitors on telomere length and telomerase activity in two immortalized human cell lines.

The ribonucleoprotein telomerase, a specialized cellular reverse transcriptase, synthesizes one strand of the telomeric DNA of eukaryotes. We analyzed telomere maintenance in two immortalized human cell lines: the B-cell line JY616 and the T-cell line Jurkat E6-1, and determined whether known inhibi...

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Detalles Bibliográficos
Main Authors: Strahl, C, Blackburn, E H
Formato: Artigo
Idioma:Inglês
Publicado: 1996
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC230978/
https://ncbi.nlm.nih.gov/pubmed/8524329
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