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Effects of reverse transcriptase inhibitors on telomere length and telomerase activity in two immortalized human cell lines.

The ribonucleoprotein telomerase, a specialized cellular reverse transcriptase, synthesizes one strand of the telomeric DNA of eukaryotes. We analyzed telomere maintenance in two immortalized human cell lines: the B-cell line JY616 and the T-cell line Jurkat E6-1, and determined whether known inhibi...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Principais autores: Strahl, C, Blackburn, E H
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1996
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230978/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8524329/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.1.53
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