Ornithine decarboxylase- and ras-induced cell transformations: reversal by protein tyrosine kinase inhibitors and role of pp130CAS.

We have found that overexpression of human ornithine decarboxylase (ODC) induces cell transformation in NIH 3T3 and Rat-1 cells (M. Auvinen, A. Paasinen, L. C. Andersson, and E. Hölttä, Nature (London) 360:355-358, 1992). The ODC-transformed cells display increased levels of tyrosine phosphorylation...

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Autors principals: Auvinen, M, Paasinen-Sohns, A, Hirai, H, Andersson, L C, Hölttä, E
Format: Artigo
Idioma:Inglês
Publicat: 1995
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC230904/
https://ncbi.nlm.nih.gov/pubmed/8524216
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