Modulation of tRNA(iMet), eIF-2, and eIF-2B expression shows that GCN4 translation is inversely coupled to the level of eIF-2.GTP.Met-tRNA(iMet) ternary complexes.

To understand how phosphorylation of eukaryotic translation initiation factor (eIF)-2 alpha in Saccharomyces cerevisiae stimulates GCN4 mRNA translation while at the same time inhibiting general translation initiation, we examined the effects of altering the gene dosage of initiator tRNA(Met), eIF-2...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Dever, T E, Yang, W, Aström, S, Byström, A S, Hinnebusch, A G
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230887/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7565788/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.11.6351
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