The yeast SEN3 gene encodes a regulatory subunit of the 26S proteasome complex required for ubiquitin-dependent protein degradation in vivo.

The yeast Sen1 protein was discovered by virtue of its role in tRNA splicing in vitro. To help determine the role of Sen1 in vivo, we attempted to overexpress the protein in yeast cells. However, cells with a high-copy SEN1-bearing plasmid, although expressing elevated amounts of SEN1 mRNA, show lit...

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Publicado en:	Mol Cell Biol
Autores principales:	DeMarini, D J, Papa, F R, Swaminathan, S, Ursic, D, Rasmussen, T P, Culbertson, M R, Hochstrasser, M
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Taylor & Francis 1995
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230883/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7565784/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.11.6311
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