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Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint.

A cdc13 temperature-sensitive mutant of Saccharomyces cerevisiae arrests in the G2 phase of the cell cycle at the restrictive temperature as a result of DNA damage that activates the RAD9 checkpoint. The DNA lesions present after a failure of Cdc13p function appear to be located almost exclusively i...

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Bibliografske podrobnosti
izdano v:Mol Cell Biol
Principais autores: Garvik, B, Carson, M, Hartwell, L
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 1995
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230864/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7565765/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.11.6128
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