Evidence for a G2 checkpoint in p53-independent apoptosis induction by X-irradiation.

The p53 tumor suppressor gene is thought to be required for the induction of programmed cell death (apoptosis) initiated by DNA damage. We show here, however, that the human promyelocytic leukemia cell line HL-60, which is known to be deficient in p53 because of large deletions in the p53 gene, can...

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Bibliografiske detaljer
Main Authors: Han, Z, Chatterjee, D, He, D M, Early, J, Pantazis, P, Wyche, J H, Hendrickson, E A
Format: Artigo
Sprog:Inglês
Udgivet: 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC230836/
https://ncbi.nlm.nih.gov/pubmed/7565737
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