A truncated herpes simplex virus thymidine kinase phosphorylates thymidine and nucleoside analogs and does not cause sterility in transgenic mice.

Dividing eukaryotic cells expressing the herpes simplex virus type 1 thymidine kinase (TK) gene are sensitive to the cytotoxic effect of nucleoside analogs such as acyclovir or ganciclovir (GCV). Transgenic mice with cell-targeted expression of this conditional toxin have been used to create animals...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Salomon, B, Maury, S, Loubière, L, Caruso, M, Onclercq, R, Klatzmann, D
Format: Artigo
Jezik:Inglês
Izdano: 1995
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC230780/
https://ncbi.nlm.nih.gov/pubmed/7565681
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki