A proline-rich sequence unique to MEK1 and MEK2 is required for raf binding and regulates MEK function.

Mammalian MEK1 and MEK2 contain a proline-rich (PR) sequence that is absent both from the yeast homologs Ste7 and Byr1 and from a recently cloned activator of the JNK/stress-activated protein kinases, SEK1/MKK4. Since this PR sequence occurs in MEKs that are regulated by Raf family enzymes but is mi...

Descrición completa

Detalles Bibliográficos

Publicado en:	Mol Cell Biol
Principais autores:	Catling, A D, Schaeffer, H J, Reuter, C W, Reddy, G R, Weber, M J
Formato:	Artigo
Idioma:	Inglês
Publicado:	Taylor & Francis 1995
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230769/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7565670/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.10.5214
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!