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The translation initiation factor eIF-4E binds to a common motif shared by the translation factor eIF-4 gamma and the translational repressors 4E-binding proteins.

Eukaryotic translation initiation factor 4E (eIF-4E), which possesses cap-binding activity, functions in the recruitment of mRNA to polysomes as part of a three-subunit complex, eIF-4F (cap-binding complex). eIF-4E is the least abundant of all translation initiation factors and a target of growth re...

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Publicat a:Mol Cell Biol
Autors principals: Mader, S, Lee, H, Pause, A, Sonenberg, N
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1995
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230746/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7651417/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.9.4990
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