The monomer-binding orphan receptor Rev-Erb represses transcription as a dimer on a novel direct repeat.
Rev-Erb is an orphan nuclear receptor which binds as a monomer to the thyroid/retinoic acid receptor half-site AGGTCA flanked 5' by an A/T-rich sequence, referred to here as a Rev monomer site. Fusion of Rev-Erb to the DNA binding domain of yeast GAL4 strongly repressed basal transcription of a GAL4...
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| Pubblicato in: | Mol Cell Biol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
1995
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230723/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7651396/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.9.4791 |
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