Stereochemical selectivity of group II intron splicing, reverse splicing, and hydrolysis reactions.

We have previously shown, using phosphorothioate substitutions at splice site, that both transesterification steps of group II intron self-splicing proceed, by stereochemical inversion, with an Sp but not an Rp phosphorothioate. Under alternative reaction conditions or with various intron fragments,...

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Detalles Bibliográficos

Publicado en:	Mol Cell Biol
Autores principales:	Podar, M, Perlman, P S, Padgett, R A
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Taylor & Francis 1995
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230686/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7542746/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.8.4466
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