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Regulation of Raf-1 and Raf-1 mutants by Ras-dependent and Ras-independent mechanisms in vitro.

The serine/threonine kinase Raf-1 functions downstream from Ras to activate mitogen-activated protein kinase kinase, but the mechanisms of Raf-1 activation are incompletely understood. To dissect these mechanisms, wild-type and mutant Raf-1 proteins were studied in an in vitro system with purified p...

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Publicat a:Mol Cell Biol
Autors principals: Dent, P, Reardon, D B, Morrison, D K, Sturgill, T W
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1995
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230651/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7623807/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.8.4125
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