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RAG2 is regulated differentially in B and T cells by elements 5′ of the promoter

To study RAG2 gene regulation in vivo, we developed a blastocyst complementation method in which RAG2-deficient embryonic stem cells were transfected with genomic clones containing RAG2 and then assessed for their ability to generate lymphocytes. A RAG2 genomic clone that contained only the RAG2 pro...

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Detalhes bibliográficos
Main Authors: Monroe, Robert J., Chen, Feng, Ferrini, Roger, Davidson, Laurie, Alt, Frederick W.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC23063/
https://ncbi.nlm.nih.gov/pubmed/10535988
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