Inhibition of cellular proliferation by the Wilms' tumor suppressor WT1 is associated with suppression of insulin-like growth factor I receptor gene expression.

We have investigated the regulation of the insulin-like growth factor I receptor (IGF-I-R) gene promoter by the Wilms' tumor suppressor WT1 in intact cells. The levels of endogenous IGF-I-R mRNA and the activity of IGF-I-R gene promoter fragments in luciferase reporter constructs were found to be si...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Werner, H, Shen-Orr, Z, Rauscher, F J, Morris, J F, Roberts, C T, LeRoith, D
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230588/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7791758/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.7.3516
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