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Generation of Tumor-Infiltrating Lymphocyte Cultures for Use in Adoptive Transfer Therapy for Melanoma Patients

The generation of T lymphocytes with specific reactivity against tumor antigens is a prerequisite for effective adoptive transfer therapies. Melanoma-specific lymphocyte cultures can be established from tumor infiltrating lymphocytes (TILs) by in vitro culture in high levels of IL-2. We have optimiz...

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Detalhes bibliográficos
Main Authors: Dudley, Mark E., Wunderlich, John R., Shelton, Thomas E., Even, Jos, Rosenberg, Steven A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2305721/
https://ncbi.nlm.nih.gov/pubmed/12843795
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