Interleukin-2 triggers a novel phosphatidylinositol 3-kinase-dependent MEK activation pathway.

Phosphatidylinositol 3-kinase (PI3-K) has been implicated as a signal-transducing component in interleukin-2 (IL-2)-induced mitogenesis. However, the function of this lipid kinase in regulating IL-2-triggered downstream events has remained obscure. Using the potent and specific PI3-K inhibitor, wort...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Karnitz, L M, Burns, L A, Sutor, S L, Blenis, J, Abraham, R T
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230536/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7760801/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.6.3049
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