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The Chinese hamster dihydrofolate reductase origin consists of multiple potential nascent-strand start sites.

Previous two-dimensional gel replicon-mapping studies on the amplified dihydrofolate reductase (DHFR) domain in CHOC 400 cells suggested that replication can initiate at any of a large number of sites scattered throughout a 55-kb region lying between two convergently transcribed genes. It could be a...

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Autori principali: Dijkwel, P A, Hamlin, J L
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1995
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC230533/
https://ncbi.nlm.nih.gov/pubmed/7760799
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