Sequential mutations in the interleukin-3 (IL3)/granulocyte-macrophage colony-stimulating factor/IL5 receptor beta-subunit genes are necessary for the complete conversion to growth autonomy mediated by a truncated beta C subunit.
An amino-terminally truncated beta C receptor (beta C-R) subunit of the interleukin-3 (IL3)/granulocyte-macrophage colony-stimulating factor/IL5 receptor complex mediates factor-independent and tumorigenic growth in two spontaneous mutants of a promyelocytic cell line. The constitutive activation of...
Salvato in:
| Pubblicato in: | Mol Cell Biol |
|---|---|
| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
1995
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230469/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7739524/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.5.2402 |
| Tags: |
Nessun Tag, puoi essere il primo ad aggiungerne!!
|