Sequential mutations in the interleukin-3 (IL3)/granulocyte-macrophage colony-stimulating factor/IL5 receptor beta-subunit genes are necessary for the complete conversion to growth autonomy mediated by a truncated beta C subunit.

An amino-terminally truncated beta C receptor (beta C-R) subunit of the interleukin-3 (IL3)/granulocyte-macrophage colony-stimulating factor/IL5 receptor complex mediates factor-independent and tumorigenic growth in two spontaneous mutants of a promyelocytic cell line. The constitutive activation of...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Hannemann, J, Hara, T, Kawai, M, Miyajima, A, Ostertag, W, Stocking, C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230469/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7739524/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.5.2402
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