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Tumor necrosis factor alpha-induced apoptosis in human neuronal cells: protection by the antioxidant N-acetylcysteine and the genes bcl-2 and crmA.

Tumor necrosis factor alpha (TNF-alpha) is a candidate human immunodeficiency virus type 1-induced neurotoxin that contributes to the pathogenesis of AIDS dementia complex. We report here on the effects of exogenous TNF-alpha on SK-N-MC human neuroblastoma cells differentiated to a neuronal phenotyp...

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Udgivet i:Mol Cell Biol
Principais autores: Talley, A K, Dewhurst, S, Perry, S W, Dollard, S C, Gummuluru, S, Fine, S M, New, D, Epstein, L G, Gendelman, H E, Gelbard, H A
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230464/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7739519/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.5.2359
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