Tumor necrosis factor alpha-induced apoptosis in human neuronal cells: protection by the antioxidant N-acetylcysteine and the genes bcl-2 and crmA.

Tumor necrosis factor alpha (TNF-alpha) is a candidate human immunodeficiency virus type 1-induced neurotoxin that contributes to the pathogenesis of AIDS dementia complex. We report here on the effects of exogenous TNF-alpha on SK-N-MC human neuroblastoma cells differentiated to a neuronal phenotyp...

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Bibliographic Details
Main Authors: Talley, A K, Dewhurst, S, Perry, S W, Dollard, S C, Gummuluru, S, Fine, S M, New, D, Epstein, L G, Gendelman, H E, Gelbard, H A
Format: Artigo
Language:Inglês
Published: 1995
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC230464/
https://ncbi.nlm.nih.gov/pubmed/7739519
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