Stimulation of interferon and cytokine gene expression by imiquimod and stimulation by Sendai virus utilize similar signal transduction pathways.

The imidazoquinolineamine derivative 1-(2-methyl propyl)-1H-imidazole [4,5-c]quinoline-4-amine (imiquimod) has been shown to induce alpha interferon (IFN-alpha) synthesis both in vivo and in peripheral blood mononuclear cells in vitro. In this study, we show that, in these cells, imiquimod induces e...

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Détails bibliographiques
Auteurs principaux: Megyeri, K, Au, W C, Rosztoczy, I, Raj, N B, Miller, R L, Tomai, M A, Pitha, P M
Format: Artigo
Langue:Inglês
Publié: 1995
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC230449/
https://ncbi.nlm.nih.gov/pubmed/7534379
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