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Stimulation of interferon and cytokine gene expression by imiquimod and stimulation by Sendai virus utilize similar signal transduction pathways.

The imidazoquinolineamine derivative 1-(2-methyl propyl)-1H-imidazole [4,5-c]quinoline-4-amine (imiquimod) has been shown to induce alpha interferon (IFN-alpha) synthesis both in vivo and in peripheral blood mononuclear cells in vitro. In this study, we show that, in these cells, imiquimod induces e...

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Udgivet i:Mol Cell Biol
Principais autores: Megyeri, K, Au, W C, Rosztoczy, I, Raj, N B, Miller, R L, Tomai, M A, Pitha, P M
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230449/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7534379/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.4.2207
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