Role of STAT2 in the alpha interferon signaling pathway.

We have isolated U6A, a mutant cell line which lacks the STAT2 subunit of the transcription factor interferon (IFN)-stimulated gene factor 3 (ISGF3). The response of U6A cells to IFN-alpha is almost completely defective, but the response to IFN-gamma is normal. Complementation of U6A cells with a cD...

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Autores principales: Leung, S, Qureshi, S A, Kerr, I M, Darnell, J E, Stark, G R
Formato: Artigo
Lenguaje:Inglês
Publicado: 1995
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC230354/
https://ncbi.nlm.nih.gov/pubmed/7532278
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