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A ubiquitin mutant with specific defects in DNA repair and multiubiquitination.

The degradation of many proteins involves the sequential ligation of ubiquitin molecules to the substrate to form a multiubiquitin chain linked through Lys-48 of ubiquitin. To test for the existence of alternate forms of multiubiquitin chains, we examined the effects of individually substituting eac...

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Autors principals: Spence, J, Sadis, S, Haas, A L, Finley, D
Format: Artigo
Idioma:Inglês
Publicat: 1995
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC230349/
https://ncbi.nlm.nih.gov/pubmed/7862120
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