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Propeptide and glutamate-containing substrates bound to the vitamin K-dependent carboxylase convert its vitamin K epoxidase function from an inactive to an active state

The vitamin K-dependent γ-glutamyl carboxylase catalyzes the posttranslational conversion of glutamic acid to γ-carboxyglutamic acid in precursor proteins containing the γ-carboxylation recognition site (γ-CRS). During this reaction, glutamic acid is converted to γ-carboxyglutamic acid while vitamin...

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Bibliographische Detailangaben
Hauptverfasser: Sugiura, Isamu, Furie, Bruce, Walsh, Christopher T., Furie, Barbara C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences of the USA 1997
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC23034/
https://ncbi.nlm.nih.gov/pubmed/9256436
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