P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase

Protein tyrosine phosphatases (PTPs) have long been thought to play a role in tumor suppression due to their ability to antagonize the growth promoting protein tyrosine kinases. Recently, a candidate tumor suppressor from 10q23, termed P-TEN, was isolated, and sequence homology was demonstrated with...

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Bibliografiska uppgifter
Huvudupphovsmän: Myers, Michael P., Stolarov, Javor P., Eng, Charis, Li, Jing, Wang, Steven I., Wigler, Michael H., Parsons, Ramon, Tonks, Nicholas K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences of the USA 1997
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC23024/
https://ncbi.nlm.nih.gov/pubmed/9256433
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