B-cell lines immortalized with an Epstein-Barr virus mutant lacking the Cp EBNA2 enhancer are biased toward utilization of the oriP-proximal EBNA gene promoter Wp1.

During Epstein-Barr virus (EBV) latent infection of B lymphocytes in vitro, six viral nuclear antigens (EBNAs) are expressed from one of two promoters, Cp or Wp, whose activities have previously been shown to be mutually exclusive in established lymphoblastoid cell lines. Initially after infection,...

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Библиографические подробности
Главные авторы: Yoo, L I, Mooney, M, Puglielli, M T, Speck, S H
Формат: Artigo
Язык:Inglês
Опубликовано: 1997
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC230214/
https://ncbi.nlm.nih.gov/pubmed/9371570
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