Recombinant respiratory syncytial virus from which the entire SH gene has been deleted grows efficiently in cell culture and exhibits site-specific attenuation in the respiratory tract of the mouse.

The small hydrophobic protein SH of human respiratory syncytial virus (RSV) is a short transmembrane surface protein of unknown function. A full-length cDNA of RSV strain A2 (subgroup A) antigenomic RNA was modified such that the entire SH gene, including the transcription signals and the complete m...

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Main Authors: Bukreyev, A, Whitehead, S S, Murphy, B R, Collins, P L
格式: Artigo
語言:Inglês
出版: 1997
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC230197/
https://ncbi.nlm.nih.gov/pubmed/9371553
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