Recombinant respiratory syncytial virus from which the entire SH gene has been deleted grows efficiently in cell culture and exhibits site-specific attenuation in the respiratory tract of the mouse.

The small hydrophobic protein SH of human respiratory syncytial virus (RSV) is a short transmembrane surface protein of unknown function. A full-length cDNA of RSV strain A2 (subgroup A) antigenomic RNA was modified such that the entire SH gene, including the transcription signals and the complete m...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Bukreyev, A, Whitehead, S S, Murphy, B R, Collins, P L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230197/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9371553/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.12.8973-8982.1997
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