Receptor-associated constitutive protein tyrosine phosphatase activity controls the kinase function of JAK1

Exposure of cells to protein tyrosine phosphatase (PTP) inhibitors causes an increase in the phosphotyrosine content of many cellular proteins. However, the level at which the primary signaling event is affected is still unclear. We show that Jaks are activated by tyrosine phosphorylation in cells t...

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Номзүйн дэлгэрэнгүй

-д хэвлэсэн:	Proc Natl Acad Sci U S A
Үндсэн зохиолчид:	Haque, S. Jaharul, Wu, Qian, Kammer, Winfried, Friedrich, Karlheinz, Smith, Jonathan M., Kerr, Ian M., Stark, George R., Williams, Bryan R. G.
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	National Academy of Sciences 1997
Нөхцлүүд:	Biological Sciences
Онлайн хандалт:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23014/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9238016/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.16.8563
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