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Significance of chaperonin 10-mediated inhibition of ATP hydrolysis by chaperonin 60

Chaperonins are essential for the folding of proteins in bacteria, mitochondria, and chloroplasts. We have functionally characterized the yeast mitochondrial chaperonins hsp60 and hsp10. In the presence of ADP, one molecule of hsp10 binds to hsp60 with an apparent K(d) of 0.9 nM and a second molecul...

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Autors principals: Dubaquié, Yves, Looser, Renate, Rospert, Sabine
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences of the USA 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC23004/
https://ncbi.nlm.nih.gov/pubmed/9256426
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