Calcium-independent activation of endothelial nitric oxide synthase by ceramide

The endothelial isoform of NO synthase (eNOS) is targeted to sphingolipid-enriched signal-transducing microdomains in the plasma membrane termed caveolae. Among the caveolae-targeted sphingolipids are the ceramides, a class of acylated sphingosine compounds that have been implicated in diverse cellu...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Igarashi, Junsuke, Thatte, Hemant S., Prabhakar, Prakash, Golan, David E., Michel, Thomas
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1999
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22998/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10535965/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.22.12583
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