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Calcium-independent activation of endothelial nitric oxide synthase by ceramide

The endothelial isoform of NO synthase (eNOS) is targeted to sphingolipid-enriched signal-transducing microdomains in the plasma membrane termed caveolae. Among the caveolae-targeted sphingolipids are the ceramides, a class of acylated sphingosine compounds that have been implicated in diverse cellu...

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Autors principals: Igarashi, Junsuke, Thatte, Hemant S., Prabhakar, Prakash, Golan, David E., Michel, Thomas
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC22998/
https://ncbi.nlm.nih.gov/pubmed/10535965
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