Exploring the origins of topological frustration: Design of a minimally frustrated model of fragment B of protein A
Topological frustration in an energetically unfrustrated off-lattice model of the helical protein fragment B of protein A from Staphylococcus aureus was investigated. This Gō-type model exhibited thermodynamic and kinetic signatures of a well-designed two-state folder with concurrent collapse and fo...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22965/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10535953/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.22.12512 |
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