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Structural flexibility in transcription complex formation revealed by protein–DNA photocrosslinking

The Oct-1 POU domain binds diverse DNA-sequence elements and forms a higher-order regulatory complex with the herpes simplex virus coregulator VP16. The POU domain contains two separate DNA-binding domains joined by a flexible linker. By protein–DNA photocrosslinking we show that the relative positi...

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Sonraí Bibleagrafaíochta
Main Authors: Cleary, Michele A., Pendergrast, P. Shannon, Herr, Winship
Formáid: Artigo
Teanga:Inglês
Foilsithe: The National Academy of Sciences of the USA 1997
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC22952/
https://ncbi.nlm.nih.gov/pubmed/9237997
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