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Evolution of the hepcidin gene in primates

BACKGROUND: Hepcidin/LEAP-1 is an iron regulatory hormone originally identified as an antimicrobial peptide. As part of a systematic analysis of the evolution of host defense peptides in primates, we have sequenced the orthologous gene from 14 species of non-human primates. RESULTS: The sequence of...

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Bibliografiske detaljer
Main Authors: Segat, Ludovica, Pontillo, Alessandra, Milanese, Michele, Tossi, Alessandro, Crovella, Sergio
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2294130/
https://ncbi.nlm.nih.gov/pubmed/18321376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-9-120
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