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Chromosomal evolution of the PKD1 gene family in primates

BACKGROUND: The autosomal dominant polycystic kidney disease (ADPKD) is mostly caused by mutations in the PKD1 (polycystic kidney disease 1) gene located in 16p13.3. Moreover, there are six pseudogenes of PKD1 that are located proximal to the master gene in 16p13.1. In contrast, no pseudogene could...

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Bibliografische gegevens
Hoofdauteurs: Kirsch, Stefan, Pasantes, Juanjo, Wolf, Andreas, Bogdanova, Nadia, Münch, Claudia, Pennekamp, Petra, Krawczak, Michael, Dworniczak, Bernd, Schempp, Werner
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2564946/
https://ncbi.nlm.nih.gov/pubmed/18822117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-8-263
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