Three-dimensional structure of NADPH–cytochrome P450 reductase: Prototype for FMN- and FAD-containing enzymes

Microsomal NADPH–cytochrome P450 reductase (CPR) is one of only two mammalian enzymes known to contain both FAD and FMN, the other being nitric-oxide synthase. CPR is a membrane-bound protein and catalyzes electron transfer from NADPH to all known microsomal cytochromes P450. The structure of rat li...

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Bibliographic Details

Published in:	Proc Natl Acad Sci U S A
Main Authors:	Wang, Ming, Roberts, David L., Paschke, Rosemary, Shea, Thomas M., Masters, Bettie Sue Siler, Kim, Jung-Ja P.
Format:	Artigo
Language:	Inglês
Published:	National Academy of Sciences 1997
Subjects:	Biological Sciences
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22938/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9237990/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.16.8411
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