Human cytochrome P450 3A4: enzymatic properties of a purified recombinant fusion protein containing NADPH-P450 reductase.

Human cytochrome P450 3A4 is recognized as the catalyst for the oxygen-dependent metabolism of a diverse group of medically important chemicals, including the immunosuppressive agent cyclosporin; macrolide antibiotics, such as erythromycin; drugs such as benzphetamine, nifedipine, and cocaine; and s...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Shet, M S, Fisher, C W, Holmans, P L, Estabrook, R W
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1993
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48061/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8265621/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.24.11748
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